Under the direction of Amar Singh, Ph.D., the Laboratory for Comprehensive Immune Studies investigates how the immune system works and how it can be guided to improve health. Located at the University of Minnesota’s Schulze Diabetes institute, this team focuses on understanding inflammation, infection, and transplant acceptance in ways that can lead to better treatments for diabetes and other conditions. By revealing the cellular and molecular signatures that predict transplant success or failure, this lab aims to reduce dependence on toxic lifelong immunosuppression. Their work could improve outcomes for people with type 1 diabetes receiving islet transplants and for kidney recipients, while paving the way for safer cell- and tissue-based therapies.
